In diabetics	ACR >2.5 mg/mmol in men and >3.5 mg/mmol in women is considered clinically significant
In non-diabetics	ACR >3 mg/mmol (confirmed) is considered clinically significant.See link.

Heavy proteinuria
ACR >70 mg/mmol (approx equivalent to PCR of >100 mg/mmol, 1gm/day)

Initial detection of proteinuria
If ACR >3 mg/mmol but <70 mg/mmol this should be confirmed by a subsequent early morning sample.
If initial ACR is >70 mg/mmol (or PCR >100 mg/mmol) a repeat sample is not required.

Additional information:

Mersey Renal Units

http://www.merseyrenalunits.nhs.uk/index.asp

NICE CKD Guidance - July 2014. Chronic kidney disease in adults: assessment and management

https://www.nice.org.uk/guidance/cg182/resources/chronic-kidney-disease-in-adults-assessment-and-management-35109809343205

Additional information on microalbumin and its clinical use can be found here: microalbumin.

Additional information on urine albumin creatinine ratio and its clinical use can be found here: urine albumin creatinine ratio.

ICE requesting info:	ICE panel name	ICE page name	Column	Comment\Advice
	Chem / Haem	Urine	1	Also on GP page

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